OUR TEAM
Paving the Way to a Brighter Future
DR. MAYANK BANSAL
Medical Director
As an Ophthalmologist, eye surgeon Dr. Bansal's dream is to help restore vision, which has been a very gratifying experience for him.
His training and work experience as a super specialist, in advanced Vitreo-Retinal Surgery at the premier Institute in India, the All India Institute of Medical Sciences (AIIMS), New Delhi, has been the solid foundation over which I strive to provide the best to my patients.
His work in Retinal Surgery at the University of California, Los Angeles, has enhanced, his in-depth understanding of eye treatment practices, as practiced in one of the top eye institutes in the world the Stein Eye Insitute, Los Angeles.
Retinal dystrophies are genetic, retinal conditions, which lead to blindness. He is pursuing research at the Council of Scientific and Industrial Research, CSIR - IGIB, New Delhi on genomic editing, using CRISPR/Cas9 in Retinal Dystrophies.
DR. DEBOJYOTI CHAKRABORTY
Scientific Advisor
Senior Scientist: Therapeutic Genome Editing, CSIR IGIB
Debojyoti Chakraborty's research focuses on the dissection and engineering of factors that modulate cellular pathways, enable rapid identification of pathogenic conditions, and generate therapeutic strategies. His lab develops genome editing tools and applies them for identifying, modelling, and correcting disease-causing mutations.
Current focus areas include:
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Therapeutic Genome Editing for the treatment of genetic disorders
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Engineered Cas systems and their applications in dissecting biological phenomena
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Stem cell derived organoid models for disease modelling
Debojyoti Chakraborty's lab has extensively characterized an orthogonal Cas9 from Francisella novicida (FnCas9) and applied it for genome editing and diagnostic applications. Working closely with clinicians, the group has shown the applicability of CRISPR based therapeutics in patient derived cells and are working towards the development of editing platforms that can be clinically translated. The group also studies certain fundamental aspects of long noncoding RNA biology and its impact in development using mini brains and spheroids as models. In recent times, the lab has contributed to the pandemic surveillance through one of the first commercially available CRISPR based diagnostic applications. Ongoing studies to make it accessible for other diseases is underway.